Mike Munhall of Ceridian Recruiting posts his experience with migrating from ColdFusion 4.5. to CFMX 7.01, a jump of 3 major versions but more like 4 since CFMX 6.1 was significantly different from 6.0 in many ways.

The ColdFusion MX 6.0 Migration Guide is a chapter of documentation intended to help cross the bridge from the C++ based server CF 5 to the Java and J2EE based CFMX 6.0. Changes in how the ColdFusion server was implemented required a migration guide and release notes to make the transisition smoother. Mike explains some unexpected problems that arose when faced with the challenge of a six year difference in ColdFusion server versions.

For your convenience, here's some links to the related documentation and release notes:

Thanks to Mike for the positive feedback of his experience with Adobe Support.